Abstract Background The importance of non-coding RNAs (ncRNAs) as fine regulators of eukaryotic gene expression has emerged by several studies focusing Transmission on microRNAs (miRNAs).miRNAs represent a newly discovered family of non coding-RNAs.They are thought to be crucial players of human hematopoiesis and related tumorigenesis and to repres
Evaluation of Australia’s Generation-Storage Requirements in a Fully Renewable Grid With Intermittent and Flexible Generation
Energy storage is crucial for grids with high renewable penetration to ensure reliable power supply during low renewable generation periods and address the intermittency associated with weather-dependent resources.However, sizing grid-scale storage presents challenges due to its interdependence on renewable generation and load profiles.This paper i
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells
Chimeric antigen receptor (CAR) redirected T cells are potent therapeutic options against hematological malignancies.The current dominant manufacturing approach for CAR T cells depends on retroviral transduction.With the advent of gene editing, insertion of a CD19-CAR into the T cell receptor (TCR) alpha constant (TRAC) locus using adeno-associated
COVID-19 Pandemic and Water, Sanitation, and Hygiene: Impacts, Challenges, and Mitigation Strategies
Background: In order to protect public health during the outbreaks of infectious diseases including the pandemic COVID-19, provision of Water, Sanitation, and Hygiene (WASH) services is important.The challenges of inaccessible WASH services along with the pandemic COVID-19 in low-income countries can lead to a devastating problem.Method: A systemat
Small Bowel Malignancy in Patient with Obscure Gastrointestinal Bleeding in Cipto Mangunkusumo Hospital, Diagnosed Using Double Balloon Enteroscopy: A Case Series
Small bowel malignancy is still a rare case as a cause of gastrointestinal bleeding.The symptoms of small bowel malignancy are not specific.One of the symptoms is obscure gastrointestinal bleeding.Obscure gastrointestinal bleeding (OGIB) is defined as recurrent or persistent gastrointestinal bleeding when the result esophagogastroduodenoscopy and c